Diffuse intrinsic pontine glioma: Insights into oncogenesis and opportunities for targeted therapy
Diffuse intrinsic pontine glioma (DIPG) is a lethal brainstem tumor that most commonly occurs in young children between the ages of five and ten.DIPG is the leading cause of brain tumor-related death in childhood, with most patients succumbing to the disease within two years of diagnosis.Attempts to improve survival through clinical trials have bee